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This entry is out of date, and will not be updated, June 2017
See also Grey literature | Health Technology Assessment International (HTAi) | Network meta-analysis | Systematic reviews | Systematic review searching
The Canadian Agency for Drugs and Technologies in Health (CADTH) / L'Agence canadienne des médicaments et des technologies de la santé (ACMTS) is a national not-for-profit producer and broker of health technology assessments and supporter of informed healthcare decision-making. To that end, CADTH provides health care decision-makers and practitioners with the evidence, analysis, advice and recommendations they need to make informed decisions. CADTH is funded jointly by Canada’s federal, provincial and territorial governments but operates independently to deliver timely, evidence-based information to health leaders about the effectiveness and efficiency of health technologies including drugs, medical devices, medical/surgical procedures and diagnostic tests. Through its wide variety of services and products, CADTH delivers information that Canada’s health care decision-makers can rely on and which is relevant to the Canadian context. CADTH is funded by the federal, provincial and territorial governments, with the exception of Quebec. CADTH's main offices are located in Ottawa, Ontario with affiliate offices in Edmonton, and Toronto. Individual liaison officers are located in most provinces.
CADTH's information providing role
To support the effective management of drugs and other health technologies in Canada, CADTH provides a range of products and services, including:
- Formulary Reviews (Common Drug Review): Objective, rigorous reviews of the clinical, cost-effectiveness, and patient evidence for drugs and formulary listing recommendations provided Canada’s publicly funded drug plans (except Quebec).
- Optimal Use Projects: Comprehensive assessments of drugs and other health technologies identified as priorities by member jurisdictions.
- Rapid Responses: Information tailored to meet urgent jurisdictional needs, to inform policy and practice decisions.
- Environmental and Horizon Scans: Alerts about new and emerging health technologies that support effective planning within the health care system.
It is important to note that many of the reports published by CADTH involve comprehensive search protocols. These protocols are widely-shared and inform the search activities of health librarians in other jurisdictions within the Canadian health system. Two popular documents in this regard are Finding the evidence: literature searching tools in support of systematic reviews and Grey Matters: a practical search tool for evidence-based medicine.
Health Technology Assessment (HTA)
Health technology assessment (HTA) is a multidisciplinary field of policy analysis. It covers the medical, social, ethical and economic implications of development, diffusion and use of health technology. Health technology is defined as prevention and rehabilitation, vaccines, pharmaceuticals and devices, medical and surgical procedures, and the systems within which health is protected and maintained. ~ Cleemput, Van Den Bruel, Kohn, Vlayen, Vinck and Thiry et al, 2007
CADTH's Top Ten Downloads
Every month, CADTH publishes a list of the most frequently downloaded reports from its website. Click here to see the current list.
- Battista RN, Côté B, Hodge MJ, Husereau D. Health technology assessment in Canada. Int J Technol Assess Health Care. 2009;25 Suppl 1:53-60.
- Chalkidou K, Tunis S, Lopert R, Rochaix L. Comparative effectiveness research and evidence-based health policy: experience from four countries. Milbank Q. 2009;87(2):339-67.
- Cleemput I, Van Den Bruel A, Kohn L, et al. Search for evidence & critical appraisal: health technology assessment (HTA). Brussels: 2007.
- DeJean D, Giacomini M, Schwartz L, Miller FA. Ethics in Canadian health technology assessment: a descriptive review. Int J Technol Assess Health Care. 2009; 25(4): 463-9.
- Docteur E, Berenson R. How will comparative effectiveness research affect the quality of health care? Washington, D.C.
- Hailey DM. Health technology assessment in Canada: diversity and evolution. Med J Aust. 2007; 187(5): 286-8.
- Husereau D, Boucher M, Noorani H. Priority setting for health technology assessment at CADTH. Int J Technol Assess Health Care. 2010; 26(3): 341-7.
- Lehoux P, Tailliez S, Denis JL, Hivon M. Redefining health technology assessment in Canada: diversification of products and contextualization of findings. Int J Technol Assess Health Care. 2004; 20(3): 325-36.
- McDaid D. Co-ordinating health technology assessment in Canada: a European perspective. Health Policy. 2003; 63(2): 205-13.
- Menon D, Topfer LA. Health technology assessment in Canada. A decade in review. Int J Technol Assess Health Care. 2000; 16(3): 896-902.
- Menon D, Stafinski T. Health technology assessment in Canada: 20 years strong? Value Health. 2009; 12 Suppl 2: S14-9.
- Sampson M, McGowan J, Lefebvre C, Moher D, Grimshaw J. PRESS: Peer Review of Electronic Search Strategies. Ottawa: Canadian Agency for Drugs and Technologies in Health; 2008.
- Tarride JE, McCarron CE, Lim M, Bowen JM, Blackhouse G, Hopkins R, O'Reilly D, Xie F, Goeree R. Economic evaluations conducted by Canadian health technology assessment agencies: where do we stand? Int J Technol Assess Health Care. 2008; 24(4): 437-44.
- Xie F, Bowen JM, Sutherland SC, Burke N, Blackhouse G, Tarride JE, O'Reilly D, Goeree R. Using health technology assessment to support evidence-based decision-making in Canada: an academic perspective. Expert Rev Pharmacoecon Outcomes Res. 2011;11(5):513-21.